Amastin Knockdown in Leishmania braziliensis Affects Parasite-Macrophage Interaction and Results in Impaired Viability of Intracellular Amastigotes

Leishmaniasis, a human parasitic disease with manifestations ranging from cutaneous ulcerations to fatal visceral infection, is caused by several Leishmania species. These protozoan parasites replicate as extracellular, flagellated promastigotes in the gut of a sandfly vector and as amastigotes insi...

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Udgivet i:PLoS Pathog
Main Authors: de Paiva, Rita Marcia Cardoso, Grazielle-Silva, Viviane, Cardoso, Mariana Santos, Nakagaki, Brenda Naemi, Mendonça-Neto, Rondon Pessoa, Canavaci, Adriana Monte Cassiano, Souza Melo, Normanda, Martinelli, Patrícia Massara, Fernandes, Ana Paula, daRocha, Wanderson Duarte, Teixeira, Santuza M. R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671664/
https://ncbi.nlm.nih.gov/pubmed/26641088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005296
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