Amastin Knockdown in Leishmania braziliensis Affects Parasite-Macrophage Interaction and Results in Impaired Viability of Intracellular Amastigotes

Leishmaniasis, a human parasitic disease with manifestations ranging from cutaneous ulcerations to fatal visceral infection, is caused by several Leishmania species. These protozoan parasites replicate as extracellular, flagellated promastigotes in the gut of a sandfly vector and as amastigotes insi...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: de Paiva, Rita Marcia Cardoso, Grazielle-Silva, Viviane, Cardoso, Mariana Santos, Nakagaki, Brenda Naemi, Mendonça-Neto, Rondon Pessoa, Canavaci, Adriana Monte Cassiano, Souza Melo, Normanda, Martinelli, Patrícia Massara, Fernandes, Ana Paula, daRocha, Wanderson Duarte, Teixeira, Santuza M. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671664/
https://ncbi.nlm.nih.gov/pubmed/26641088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005296
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