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Necrosis-Induced Sterile Inflammation Mediated by Interleukin-1α in Retinal Pigment Epithelial Cells

Endogenous danger signals released from necrotic cells contribute to retinal inflammation. We have now investigated the effects of necrotic cell extracts prepared from ARPE-19 human retinal pigment epithelial cells (ANCE) on the release of proinflammatory cytokines and chemokines by healthy ARPE-19...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Yang, Kimura, Kazuhiro, Orita, Tomoko, Sonoda, Koh-Hei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671579/
https://ncbi.nlm.nih.gov/pubmed/26641100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144460
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