Inhibition of epithelial–mesenchymal transition in retinal pigment epithelial cells by a retinoic acid receptor-α agonist

Epithelial–mesenchymal transition (EMT) in retinal pigment epithelial (RPE) cells plays a key role in proliferative retinal diseases such as age-related macular degeneration by contributing to subretinal fibrosis. To investigate the potential role of retinoic acid receptor-α (RAR-α) signaling in thi...

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Publicado no:Sci Rep
Main Authors: Kobayashi, Yuka, Tokuda, Kazuhiro, Yamashiro, Chiemi, Higashijima, Fumiaki, Yoshimoto, Takuya, Ota, Manami, Ogata, Tadahiko, Ashimori, Atsushige, Hatano, Makoto, Kobayashi, Masaaki, Uchi, Sho-Hei, Wakuta, Makiko, Kimura, Kazuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178299/
https://ncbi.nlm.nih.gov/pubmed/34088917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90618-4
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