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Evaluation and Validation of Assembling Corrected PacBio Long Reads for Microbial Genome Completion via Hybrid Approaches

Despite the ever-increasing output of next-generation sequencing data along with developing assemblers, dozens to hundreds of gaps still exist in de novo microbial assemblies due to uneven coverage and large genomic repeats. Third-generation single-molecule, real-time (SMRT) sequencing technology av...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lin, Hsin-Hung, Liao, Yu-Chieh
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671558/
https://ncbi.nlm.nih.gov/pubmed/26641475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144305
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