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Impaired Integrin β3 Delays Endothelial Cell Regeneration and Contributes to Arteriovenous Graft Failure in mice

OBJECTIVE: Neointima formation is associated with stenosis and subsequent thrombosis in arteriovenous grafts (AVG). A role of integrin β3 in the neointima formation of AVGs remains poorly understood. APPROACH AND RESULTS: In integrin β3(−/−) mice, we found significantly accelerated occlusion of AVGs...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Liang, Ming, Wang, Yun, Liang, Anlin, Dong, Jin-Fei, Du, Jie, Cheng, Jizhong
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671198/
https://ncbi.nlm.nih.gov/pubmed/25614287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.305089
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