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Stanniocalcin-1 inhibits thrombin-induced signaling and protects from bleomycin-induced lung injury
Thrombin-induced and proteinase-activated receptor 1 (PAR1)-mediated signaling increases ROS production, activates ERK, and promotes inflammation and fibroblast proliferation in bleomycin-induced lung injury. Stanniocalcin-1 (STC1) activates anti-oxidant pathways, inhibits inflammation and provides...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4671147/ https://ncbi.nlm.nih.gov/pubmed/26640170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18117 |
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