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Knockout of silent information regulator 2 (SIRT2) preserves neurological function after experimental stroke in mice

Sirtuin-2 (Sirt2) is a member of the NAD(+)-dependent protein deacetylase family. Various members of the sirtuin class have been found to be involved in processes related to longevity, regulation of inflammation, and neuroprotection. Induction of Sirt2 mRNA was found in the whole hemisphere after ex...

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Detalles Bibliográficos
Publicado en:J Cereb Blood Flow Metab
Autores principales: Krey, Lea, Lühder, Fred, Kusch, Kathrin, Czech-Zechmeister, Bozena, Könnecke, Birte, Outeiro, Tiago Fleming, Trendelenburg, George
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671131/
https://ncbi.nlm.nih.gov/pubmed/26219598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.178
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