Synovial Regulatory T Cells Occupy a Discrete TCR Niche in Human Arthritis and Require Local Signals To Stabilize FOXP3 Protein Expression

Although there is great interest in harnessing the immunosuppressive potential of FOXP3(+) regulatory T cells (Tregs) for treating autoimmunity, a sizeable knowledge gap exists regarding Treg fate in human disease. In juvenile idiopathic arthritis (JIA) patients, we have previously reported that aty...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:J Immunol
Huvudupphovsmän: Bending, David, Giannakopoulou, Eirini, Lom, Hannah, Wedderburn, Lucy R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: AAI 2015
Ämnen:
Clinical and Human Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671090/
https://ncbi.nlm.nih.gov/pubmed/26561546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500391
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk