Chemosensitization of HepG2 cells by suppression of NF-κB/p65 gene transcription with specific-siRNA

AIM: To investigate small interfering RNA (siRNA)-mediated inhibition of nuclear factor-kappa B (NF-κB) activation and multidrug-resistant (MDR) phenotype formation in human HepG2 cells. METHODS: Total RNA was extracted from human HepG2 or LO2 cells. NF-κB/p65 mRNA was amplified by nested reverse tr...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Shi, Yun, Wang, Si-Ye, Yao, Min, Sai, Wen-Li, Wu, Wei, Yang, Jun-Ling, Cai, Yin, Zheng, Wen-Jie, Yao, Deng-Fu
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2015
Assuntos:
Basic Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671036/
https://ncbi.nlm.nih.gov/pubmed/26668505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i45.12814
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