TLR4 drives the pathogenesis of acquired cholesteatoma by promoting local inflammation and bone destruction

Acquired cholesteatoma is a chronic inflammatory disease characterized by both hyperkeratinized squamous epithelial overgrowth and bone destruction. Toll-like receptor (TLR) activation and subsequent inflammatory cytokine production are closely associated with inflammatory bone disease. However, the...

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Publicado en:Sci Rep
Main Authors: Si, Yu, Chen, Yu Bin, Chen, Sui Jun, Zheng, Yi Qing, Liu, Xiang, Liu, Yi, Jiang, Huai Li, Xu, Guo, Li, Zhuo Hao, Huang, Qiu Hong, Xiong, Hao, Zhang, Zhi Gang
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671024/
https://ncbi.nlm.nih.gov/pubmed/26639190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16683
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