Multiple region whole-exome sequencing reveals dramatically evolving intratumor genomic heterogeneity in esophageal squamous cell carcinoma

Cancer is a disease of genome instability and genomic alterations; now, genomic heterogeneity is rapidly emerging as a defining feature of cancer, both within and between tumors. Motivation for our pilot study of tumor heterogeneity in esophageal squamous cell carcinoma (ESCC) is that it is not well...

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Publicat a:Oncogenesis
Autors principals: Cao, W, Wu, W, Yan, M, Tian, F, Ma, C, Zhang, Q, Li, X, Han, P, Liu, Z, Gu, J, Biddle, F G
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670960/
https://ncbi.nlm.nih.gov/pubmed/26619400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2015.34
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