Phase Ib Randomized, Double-Blinded, Placebo-Controlled, Dose Escalation Study of Polyphenon E in Patients with Barrett’s Esophagus

This study was conducted to determine the safety and efficacy of the green-tea derived Polyphenon E (Poly E) in patients with Barrett’s Esophagus (BE). Subjects were randomized to a 6-month, twice daily (BID) oral treatment of placebo or Poly E (200 mg, 400 mg, or 600 mg). Endoscopic evaluation, inc...

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Publicado en:Cancer Prev Res (Phila)
Main Authors: Joe, Andrew K., Schnoll-Sussman, Felice, Bresalier, Robert S., Abrams, Julian A., Hibshoosh, Hanina, Cheung, Ken, Friedman, Richard A., Yang, Chung S., Milne, Ginger L., Liu, Diane D., Lee, J. Jack, Abdul, Kazeem, Bigg, Michelle, Foreman, Jessica, Su, Tao, Wang, Xiaomei, Ahmed, Aqeel, Neugut, Alfred I., Akpa, Esther, Lippman, Scott M., Perloff, Marjorie, Brown, Powel H., Lightdale, Charles J.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670789/
https://ncbi.nlm.nih.gov/pubmed/26471236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-14-0274-T
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