Juglanthraquinone C Induces Intracellular ROS Increase and Apoptosis by Activating the Akt/Foxo Signal Pathway in HCC Cells

Juglanthraquinone C (JC), a naturally occurring anthraquinone extracted from Juglans mandshurica, could induce apoptosis of cancer cells. This study aims to investigate the detailed cytotoxicity mechanism of JC in HepG2 and BEL-7402 cells. The Affymetrix HG-U133 Plus 2.0 arrays were first used to an...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Hou, Ya-Qin, Yao, Yao, Bao, Yong-Li, Song, Zhen-Bo, Yang, Cheng, Gao, Xiu-Li, Zhang, Wen-Jing, Sun, Lu-Guo, Yu, Chun-Lei, Huang, Yan-Xin, Wang, Guan-Nan, Li, Yu-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670685/
https://ncbi.nlm.nih.gov/pubmed/26682007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4941623
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