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Severely exacerbated neuromyelitis optica rat model with extensive astrocytopathy by high affinity anti-aquaporin-4 monoclonal antibody
INTRODUCTION: Neuromyelitis optica (NMO), an autoimmune astrocytopathic disease associated with anti-aquaporin-4 (AQP4) antibody, is characterized by extensive necrotic lesions preferentially involving the optic nerves and spinal cord. However, previous in-vivo experimental models injecting human an...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Acta Neuropathol Commun |
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Κύριοι συγγραφείς: | , , , , , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
BioMed Central
2015
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4670539/ https://ncbi.nlm.nih.gov/pubmed/26637322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0259-2 |
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