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Rare variants analysis using penalization methods for whole genome sequence data

BACKGROUND: Availability of affordable and accessible whole genome sequencing for biomedical applications poses a number of statistical challenges and opportunities, particularly related to the analysis of rare variants and sparseness of the data. Although efforts have been devoted to address these...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Yazdani, Akram, Yazdani, Azam, Boerwinkle, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670502/
https://ncbi.nlm.nih.gov/pubmed/26637205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0825-4
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