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Absence of the intestinal microbiota exacerbates hepatobiliary disease in a murine model of primary sclerosing cholangitis
INTRODUCTION: Primary sclerosing cholangitis (PSC) is a chronic, idiopathic, fibro-inflammatory cholangiopathy. The role of the microbiota in PSC etiopathogenesis may be fundamentally important yet remains obscure. We tested the hypothesis that germ-free (GF) mdr2(−/−) mice develop a distinct PSC ph...
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| Veröffentlicht in: | Hepatology |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4670294/ https://ncbi.nlm.nih.gov/pubmed/26044703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27927 |
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