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Uterine Carcinomas in Tetrabromobisphenol A-Exposed Wistar Han Rats Harbor Increased Tp53 Mutations and Mimic High-Grade Type I Endometrial Carcinomas in Women

Endometrial carcinoma is the most common gynecologic malignancy is the United States, and accounts for 6% of all cancers in women. The disease is classified as Type I or Type II based on clinicopathologic and molecular features. It is a multifactorial disease with a number of risk factors, including...

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Vydáno v:Toxicol Pathol
Hlavní autoři: Harvey, Janice B., Osborne, Tanasa S., Hong, Hue-Hua L., Bhusari, Sachin, Ton, Tai-Vu, Pandiri, Arun R., Masinde, Tiwanda, Dunnick, June, Peddada, Shyamal, Elmore, Susan, Hoenerhoff, Mark J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670270/
https://ncbi.nlm.nih.gov/pubmed/26353976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623315599256
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