A Single Intravitreal Injection of Ranibizumab Provides No Neuroprotection in a Nonhuman Primate Model of Moderate-to-Severe Nonarteritic Anterior Ischemic Optic Neuropathy

PURPOSE: Ranibizumab, a vascular endothelial growth factor-antagonist, is said to be neuroprotective when injected intravitreally in patients with nonarteritic anterior ischemic optic neuropathy (NAION). We evaluated the efficacy of a single intravitreal (IVT) injection of ranibizumab in a nonhuman...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Miller, Neil R., Johnson, Mary A., Nolan, Theresa, Guo, Yan, Bernstein, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
Assuntos:
Eye Movements, Strabismus, Amblyopia and Neuro-Ophthalmology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669855/
https://ncbi.nlm.nih.gov/pubmed/26624498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-18015
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