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Sustained Neuroprotection From a Single Intravitreal Injection of PGJ(2) in a Nonhuman Primate Model of Nonarteritic Anterior Ischemic Optic Neuropathy

PURPOSE. Prostaglandin J2 (PGJ(2)) is neuroprotective in a murine model of nonarteritic anterior ischemic optic neuropathy (NAION). After assessing for potential toxicity, we evaluated the efficacy of a single intravitreal (IVT) injection of PGJ(2) in a nonhuman primate model of NAION (pNAION). METH...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Miller, Neil R., Johnson, Mary A., Nolan, Theresa, Guo, Yan, Bernstein, Alexander M., Bernstein, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222271/
https://ncbi.nlm.nih.gov/pubmed/25298416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14063
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