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Oxidative damage to RPA limits the nucleotide excision repair capacity of human cells

Nucleotide excision repair (NER) protects against sunlight-induced skin cancer. Defective NER is associated with photosensitivity and a high skin cancer incidence. Some clinical treatments that cause photosensitivity can also increase skin cancer risk. Among these, the immunosuppressant azathioprine...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Invest Dermatol
Prif Awduron: Guven, Melisa, Brem, Reto, Macpherson, Peter, Peacock, Matthew, Karran, Peter
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669849/
https://ncbi.nlm.nih.gov/pubmed/26134950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.255
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