Glycation of vitronectin inhibits VEGF-induced angiogenesis by uncoupling VEGF receptor-2–αvβ3 integrin cross-talk

Glycation of vessel wall proteins is thought to have an important role in the pathogenesis of vascular complications in diabetes mellitus. However, no previous study has implicated glycated vitronectin (VN) in the control of vascular endothelial growth factor (VEGF) signaling. To explore whether the...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, L, Zhang, X, Pang, N, Xiao, L, Li, Y, Chen, N, Ren, M, Deng, X, Wu, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669844/
https://ncbi.nlm.nih.gov/pubmed/26111058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.174
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