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Chloride transporter KCC2-dependent neuroprotection depends on the N-terminal protein domain

Neurodegeneration is a serious issue of neurodegenerative diseases including epilepsy. Downregulation of the chloride transporter KCC2 in the epileptic tissue may not only affect regulation of the polarity of GABAergic synaptic transmission but also neuronal survival. Here, we addressed the mechanis...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Winkelmann, A, Semtner, M, Meier, J C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669822/
https://ncbi.nlm.nih.gov/pubmed/26043076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.127
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