Akt phosphorylates Prohibitin 1 to mediate its mitochondrial localization and promote proliferation of bladder cancer cells

Bladder cancer (BC) is very common and associated with significant morbidity and mortality, though the molecular underpinnings of its origination and progression remain poorly understood. In this study, we demonstrate that Prohibitin 1 (PHB) was overexpressed in human BC tissues and that PHB upregul...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Jiang, L, Dong, P, Zhang, Z, Li, C, Li, Y, Liao, Y, Li, X, Wu, Z, Guo, S, Mai, S, Xie, D, Liu, Z, Zhou, F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669803/
https://ncbi.nlm.nih.gov/pubmed/25719244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.40
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