Mitochondrial Lon regulates apoptosis through the association with Hsp60–mtHsp70 complex

Human Lon protease is a mitochondrial matrix protein with several functions, including protein degradation, mitochondrial DNA (mtDNA) binding, and chaperone activity. Lon is currently emerging as an important regulator of mitochondria-contributed tumorigenesis due to its overexpression in cancer cel...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Kao, T-Y, Chiu, Y-C, Fang, W-C, Cheng, C-W, Kuo, C-Y, Juan, H-F, Wu, S-H, Lee, A Y-L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669791/
https://ncbi.nlm.nih.gov/pubmed/25675302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.9
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