Sonic hedgehog through Gli2 and Gli3 is required for the proper development of placental labyrinth

Sonic hedgehog (Shh) functions as a conserved morphogen in the development of various organs in metazoans ranging from Drosophila to humans. Here, we have investigated the potential roles and underlying mechanisms of Shh signaling in murine placentation. Immunostaining revealed the abundant expressi...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Pan, Y B, Gong, Y, Ruan, H F, Pan, L Y, Wu, X K, Tang, C, Wang, C J, Zhu, H B, Zhang, Z M, Tang, L F, Zou, C C, Wang, H B, Wu, X M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669788/
https://ncbi.nlm.nih.gov/pubmed/25695606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.28
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