Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway

High serum lipopolysaccharide (LPS) activity in normoalbuminuric patients with type 1 diabetes (T1D) predicts the progression of diabetic nephropathy (DN), but the mechanisms behind this remain unclear. We observed that treatment of cultured human podocytes with sera from normoalbuminuric T1D patien...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Saurus, P, Kuusela, S, Lehtonen, E, Hyvönen, M E, Ristola, M, Fogarty, C L, Tienari, J, Lassenius, M I, Forsblom, C, Lehto, M, Saleem, M A, Groop, P-H, Holthöfer, H, Lehtonen, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669704/
https://ncbi.nlm.nih.gov/pubmed/25950482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.125
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