PD-1 and Tim-3 pathways are associated with regulatory CD8(+) T-cell function in decidua and maintenance of normal pregnancy

CD8(+) T cells are critical in the balance between fetal tolerance and antiviral immunity. T-cell immunoglobulin mucin-3 (Tim-3) and programmed cell death-1 (PD-1) are important negative immune regulatory molecules involved in viral persistence and tumor metastasis. Here, we demonstrate that Tim-3(+...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, S-C, Li, Y-H, Piao, H-L, Hong, X-W, Zhang, D, Xu, Y-Y, Tao, Y, Wang, Y, Yuan, M-M, Li, D-J, Du, M-R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669692/
https://ncbi.nlm.nih.gov/pubmed/25950468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.112
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados