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Computational Modeling of Kinase Inhibitor Selectivity
[Image: see text] An exhaustive computational exercise on a comprehensive set of 15 therapeutic kinase inhibitors was undertaken to identify as to which compounds hit which kinase off-targets in the human kinome. Although the kinase selectivity propensity of each inhibitor against ∼480 kinase target...
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| Udgivet i: | ACS Med Chem Lett |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical Society
2010
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4669537/ https://ncbi.nlm.nih.gov/pubmed/26677403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml1001097 |
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