Metabolomic profiles delineate mycolactone signature in Buruli ulcer disease

Infection of human skin with Mycobacterium ulcerans, the causative agent of Buruli ulcer, is associated with the systemic diffusion of a bacterial macrolide named mycolactone. Patients with progressive disease show alterations in their serum proteome, likely reflecting the inhibition of secreted pro...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Niang, Fatoumata, Sarfo, Fred S., Frimpong, Michael, Guenin-Macé, Laure, Wansbrough-Jones, Mark, Stinear, Timothy, Phillips, Richard O., Demangel, Caroline
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669498/
https://ncbi.nlm.nih.gov/pubmed/26634444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17693
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