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Evolutionary Selection on Barrier Activity: Bar1 Is an Aspartyl Protease with Novel Substrate Specificity

Peptide-based pheromones are used throughout the fungal kingdom for coordinating sexual responses between mating partners. Here, we address the properties and function of Bar1, an aspartyl protease that acts as a “barrier” and antagonist to pheromone signaling in multiple species. Candida albicans B...

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Pubblicato in:mBio
Autori principali: Jones, Stephen K., Clarke, Starlynn C., Craik, Charles S., Bennett, Richard J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Microbiology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669382/
https://ncbi.nlm.nih.gov/pubmed/26604258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01604-15
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