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Using specificity to strategically target proteases

Proteases are a family of naturally occurring enzymes in the body whose dysregulation has been implicated in numerous diseases and cancers. Their ability to selectively and catalytically turnover substrate adds both signal amplification and functionality as parameters for the detection of disease. T...

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Detalhes bibliográficos
Main Authors: Lim, Mark D., Craik, Charles S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663002/
https://ncbi.nlm.nih.gov/pubmed/18434168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.03.068
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