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Relationship between Initial Telomere Length, Initial Telomerase Activity, Age, and Replicative Capacity of Nucleus Pulposus Chondrocytes in Human Intervertebral Discs: What Is a Predictor of Replicative Potential?

There is evidence that telomere length (TL), telomerase activity (TA), and age are related to the replicative potential of human nucleus pulposus chondrocytes (NPCs). However, it has not yet been established if any of these factors can serve as predictors of the replicative potential of NPCs. To est...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Lee, Jun-Seok, Jeong, Seo-Won, Cho, Sung-Wook, Juhn, Joon-Pyo, Kim, Ki-Won
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669191/
https://ncbi.nlm.nih.gov/pubmed/26633809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144177
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