PD-L1 Blockade Differentially Impacts Regulatory T Cells from HIV-Infected Individuals Depending on Plasma Viremia

Blocking the PD-1/PD-L1 pathway has emerged as a potential therapy to restore impaired immune responses in human immunodeficiency virus (HIV)-infected individuals. Most reports have studied the impact of the PD-L1 blockade on effector cells and neglected possible effects on regulatory T cells (Treg...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Peligero, Cristina, Argilaguet, Jordi, Güerri-Fernandez, Roberto, Torres, Berta, Ligero, Carmen, Colomer, Pilar, Plana, Montserrat, Knobel, Hernando, García, Felipe, Meyerhans, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669187/
https://ncbi.nlm.nih.gov/pubmed/26633181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005270
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