PD-1(+) regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer

PD-1 blockade is a cancer immunotherapy effective in various types of cancer. In a fraction of treated patients, however, it causes rapid cancer progression called hyperprogressive disease (HPD). With our observation of HPD in ∼10% of anti–PD-1 monoclonal antibody (mAb)-treated advanced gastric canc...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Kamada, Takahiro, Togashi, Yosuke, Tay, Christopher, Ha, Danbee, Sasaki, Akinori, Nakamura, Yoshiaki, Sato, Eiichi, Fukuoka, Shota, Tada, Yasuko, Tanaka, Atsushi, Morikawa, Hiromasa, Kawazoe, Akihito, Kinoshita, Takahiro, Shitara, Kohei, Sakaguchi, Shimon, Nishikawa, Hiroyoshi
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525547/
https://ncbi.nlm.nih.gov/pubmed/31028147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1822001116
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars