Transient Cerebral Ischemia Promotes Brain Mitochondrial Dysfunction and Exacerbates Cognitive Impairments in Young 5xFAD Mice

Alzheimer's disease (AD) is heterogeneous and multifactorial neurological disorder; and the risk factors of AD still remain elusive. Recent studies have highlighted the role of vascular factors in promoting the progression of AD and have suggested that ischemic events increase the incidence of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Lu, Lin, Guo, Lan, Gauba, Esha, Tian, Jing, Wang, Lu, Tandon, Neha, Shankar, Malini, Beck, Simon J., Du, Yifeng, Du, Heng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669173/
https://ncbi.nlm.nih.gov/pubmed/26632816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144068
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