HLA-G 3’UTR Polymorphisms Impact the Prognosis of Stage II-III CRC Patients in Fluoropyrimidine-Based Treatment

An important hallmark of CRC is the evasion of immune surveillance. HLA-G is a negative regulator of host’s immune response. Overexpression of HLA-G protein in primary tumour CRC tissues has already been associated to worse prognosis; however a definition of the role of immunogenetic host background...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Garziera, Marica, Bidoli, Ettore, Cecchin, Erika, Mini, Enrico, Nobili, Stefania, Lonardi, Sara, Buonadonna, Angela, Errante, Domenico, Pella, Nicoletta, D’Andrea, Mario, De Marchi, Francesco, De Paoli, Antonino, Zanusso, Chiara, De Mattia, Elena, Tassi, Renato, Toffoli, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669157/
https://ncbi.nlm.nih.gov/pubmed/26633805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144000
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