HLA-G 3′UTR Polymorphisms Predict Drug-Induced G3-4 Toxicity Related to Folinic Acid/5-Fluorouracil/Oxaliplatin (FOLFOX4) Chemotherapy in Non-Metastatic Colorectal Cancer

Polymorphisms in drug-metabolizing enzymes might not completely explain inter-individual differences in toxicity profiles of patients with colorectal cancer (CRC) that receive folinic acid/5-fluorouracil/oxaliplatin (FOLFOX4). Recent data indicate that the immune system could contribute to FOLFOX4 o...

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Detalhes bibliográficos
Main Authors: Marica Garziera, Saverio Virdone, Elena De Mattia, Lucia Scarabel, Erika Cecchin, Jerry Polesel, Mario D’Andrea, Nicoletta Pella, Angela Buonadonna, Adolfo Favaretto, Giuseppe Toffoli
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2017-06-01
Colecção:International Journal of Molecular Sciences
Assuntos:
colorectal cancer
human leukocyte antigen-G 3′UTR
polymorphism
toxicity
folinic acid/5-fluorouracil/oxaliplatin
immunogenetics
Acesso em linha:http://www.mdpi.com/1422-0067/18/7/1366
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