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Click synthesis of a polyamidoamine dendrimer-based camptothecin prodrug
In the present work we report on the click synthesis of a new camptothecin (CPT) prodrug based on anionic polyamidoamine (PAMAM) dendrimer intended for cancer therapy. We applied ‘click’ chemistry to improve polymer-drug coupling reaction efficiency. Specifically, CPT was functionalized with a space...
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| Pubblicato in: | RSC Adv |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4669072/ https://ncbi.nlm.nih.gov/pubmed/26640689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C5RA07987J |
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