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The choice of test in phase II cancer trials assessing continuous tumour shrinkage when complete responses are expected

Traditionally, phase II cancer trials test a binary endpoint formed from a dichotomisation of the continuous change in tumour size. Directly testing the continuous endpoint provides considerable gains in power, although also results in several statistical issues. One such issue is when complete resp...

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Vydáno v:Stat Methods Med Res
Hlavní autoři: Wason, James MS, Mander, Adrian P
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668774/
https://ncbi.nlm.nih.gov/pubmed/22179821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280211432192
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