Cargando...
Loss of function of myosin chaperones triggers Hsf1-mediated transcriptional response in skeletal muscle cells
BACKGROUND: Mutations in myosin chaperones Unc45b and Hsp90aa1.1 as well as in the Unc45b-binding protein Smyd1b impair formation of myofibrils in skeletal muscle and lead to the accumulation of misfolded myosin. The concomitant transcriptional response involves up-regulation of the three genes enco...
Gardado en:
| Publicado en: | Genome Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2015
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4668643/ https://ncbi.nlm.nih.gov/pubmed/26631063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0825-8 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|