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Lack of Apobec2-related proteins causes a dystrophic muscle phenotype in zebrafish embryos

The chaperones Unc45b and Hsp90a are essential for folding of myosin in organisms ranging from worms to humans. We show here that zebrafish Unc45b, but not Hsp90a, binds to the putative cytidine deaminase Apobec2 (Apo2) in an interaction that requires the Unc45/Cro1p/She4p-related (UCS) and central...

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Détails bibliographiques
Auteurs principaux: Etard, Christelle, Roostalu, Urmas, Strähle, Uwe
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867308/
https://ncbi.nlm.nih.gov/pubmed/20440001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200912125
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