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Lack of Apobec2-related proteins causes a dystrophic muscle phenotype in zebrafish embryos

The chaperones Unc45b and Hsp90a are essential for folding of myosin in organisms ranging from worms to humans. We show here that zebrafish Unc45b, but not Hsp90a, binds to the putative cytidine deaminase Apobec2 (Apo2) in an interaction that requires the Unc45/Cro1p/She4p-related (UCS) and central...

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Detalles Bibliográficos
Main Authors: Etard, Christelle, Roostalu, Urmas, Strähle, Uwe
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867308/
https://ncbi.nlm.nih.gov/pubmed/20440001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200912125
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