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Multiple regulation pathways and pivotal biological functions of STAT3 in cancer

STAT3 is both a transcription activator and an oncogene that is tightly regulated under normal physiological conditions. However, abundant evidence indicates that STAT3 is persistently activated in several cancers, with a crucial position in tumor onset and progression. In addition to its traditiona...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yuan, Jie, Zhang, Fei, Niu, Ruifang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668392/
https://ncbi.nlm.nih.gov/pubmed/26631279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17663
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