Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets

Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel and highly pathogenic human coronavirus and has quickly spread to other countries in the Middle East, Europe, North Africa and Asia since 2012. Previous studies have shown that MERS-CoV ORF4b antagonizes the early antiviral alpha/bet...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Yang, Yang, Ye, Fei, Zhu, Na, Wang, Wenling, Deng, Yao, Zhao, Zhengdong, Tan, Wenjie
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668369/
https://ncbi.nlm.nih.gov/pubmed/26631542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17554
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