NDK Interacts with FtsZ and Converts GDP to GTP to Trigger FtsZ Polymerisation - A Novel Role for NDK

INTRODUCTION: Nucleoside diphosphate kinase (NDK), conserved across bacteria to humans, synthesises NTP from NDP and ATP. The eukaryotic homologue, the NDPK, uses ATP to phosphorylate the tubulin-bound GDP to GTP for tubulin polymerisation. The bacterial cytokinetic protein FtsZ, which is the tubuli...

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Publicado en:PLoS One
Autores principales: Mishra, Saurabh, Jakkala, Kishor, Srinivasan, Ramanujam, Arumugam, Muthu, Ranjeri, Raghavendra, Gupta, Prabuddha, Rajeswari, Haryadi, Ajitkumar, Parthasarathi
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668074/
https://ncbi.nlm.nih.gov/pubmed/26630542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143677
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