NDK Interacts with FtsZ and Converts GDP to GTP to Trigger FtsZ Polymerisation - A Novel Role for NDK

INTRODUCTION: Nucleoside diphosphate kinase (NDK), conserved across bacteria to humans, synthesises NTP from NDP and ATP. The eukaryotic homologue, the NDPK, uses ATP to phosphorylate the tubulin-bound GDP to GTP for tubulin polymerisation. The bacterial cytokinetic protein FtsZ, which is the tubuli...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Mishra, Saurabh, Jakkala, Kishor, Srinivasan, Ramanujam, Arumugam, Muthu, Ranjeri, Raghavendra, Gupta, Prabuddha, Rajeswari, Haryadi, Ajitkumar, Parthasarathi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668074/
https://ncbi.nlm.nih.gov/pubmed/26630542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143677
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