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Understanding the α-Helix to Coil Transition in Polypeptides Using Network Rigidity: Predicting Heat and Cold Denaturation in Mixed Solvent Conditions
Thermodynamic stability in polypeptides is described using a novel Distance Constraint Model (DCM). Here, microscopic interactions are represented as constraints. A topological arrangement of constraints define a mechanical framework. Each constraint in the framework is associated with an enthalpic...
Shranjeno v:
| izdano v: | Biopolymers |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4667961/ https://ncbi.nlm.nih.gov/pubmed/15307195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.20102 |
| Oznake: |
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