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Understanding the α-Helix to Coil Transition in Polypeptides Using Network Rigidity: Predicting Heat and Cold Denaturation in Mixed Solvent Conditions

Thermodynamic stability in polypeptides is described using a novel Distance Constraint Model (DCM). Here, microscopic interactions are represented as constraints. A topological arrangement of constraints define a mechanical framework. Each constraint in the framework is associated with an enthalpic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biopolymers
Prif Awduron: Jacobs, Donald J., Wood, Gregory G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667961/
https://ncbi.nlm.nih.gov/pubmed/15307195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.20102
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