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Neuritic complexity of hippocampal neurons depends on WIP‐mediated mTORC1 and Abl family kinases activities

INTRODUCTION: Neuronal morphogenesis is governed mainly by two interconnected processes, cytoskeletal reorganization, and signal transduction. The actin‐binding molecule WIP (Wiskott‐Aldrich syndrome protein [WASP]‐interacting protein) was identified as a negative regulator of neuritogenesis. Althou...

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Detalhes bibliográficos
Publicado no:Brain Behav
Main Authors: Franco‐Villanueva, Ana, Wandosell, Francisco, Antón, Inés M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667760/
https://ncbi.nlm.nih.gov/pubmed/26664784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.359
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